Nanoscale Super-Resolution Imaging with AFM-IR

• By integrating Atomic Force Microscopy with Infrared Spectroscopy we can achieve super-resolution, which lets us look into nanoscale objects!
• We can use this to gain fundamental insights about nanoscale chemistry and its variations

Publications in this Area​​

• ​Banerjee, S.; Baghel, D.; Pacheco de Oliveira, A.; Ghosh, A.  β-Carotene, a Potent Amyloid Aggregation Inhibitor, Promotes Disordered Aβ Fibrillar Structure. International Journal of Molecular Sciences, 2023, 24(6), 5175.  https://doi.org/10.3390/ijms24065175
• Banerjee, S.; Naik, T.; Baghel, D.; Ghosh, A. Intermediate Antiparallel Fibrils in Aβ40 Dutch Mutant Aggregation: Insights from Nanoscale Infrared Spectroscopy. Journal of Physical Chemistry B, 2023, 127(26), 5799. https://doi.org/10.1021/acs.jpcb.3c01869
• Banjeree, S.; Baghel, D.; Hasan Ul Iqbal, M.; Ghosh, A. Nanoscale Infrared Spectroscopy Identifies Parallel to Antiparallel β-Sheet Transformation of Aβ Fibrils. Journal of Physical Chemistry Letters, 2022, 13(45), 10522. doi.org/10.1021/acs.jpclett.2c02998
• Banjeree, S.; Ghosh, A. Structurally Distinct Polymorphs of Tau Aggregates Revealed by Nanoscale Infrared Spectroscopy. Journal of Physical Chemistry Letters, 2021, 12(45), 11035. https://doi.org/10.1021/acs.jpclett.1c02660